IndraLab

Statements

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"BRCC3 mediates inflammation and pyroptosis in cerebral ischemia/reperfusion injury by activating the NLRP6 inflammasome."
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"BRCC3 knockdown reduced the inflammation and pyroptosis caused by cerebral I/R injury and ameliorated neurological deficits in mice after MCAO."
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"18 BRCC3 can activate inflammasomes to mediate the inflammatory response."
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"However, the role of BRCC3 in modulating airway inflammation in asthma has not been investigated."
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"Conversely, the overexpression of BRCC3 in airway epithelial cells worsened DM-induced cell injury and inflammation while also enhancing the NLRP3 inflammasome and pyroptosis."
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