IndraLab

Statements


UCHL1 inhibits CD36. 4 / 4
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"Deletion of UCHL1 induces downregulation of scavenger receptor CD36 protein."

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"Based on UCHL1 mediated lipid uptake via promoting CD36 stability, we assess whether UCHL1 inhibition induced downregulation of CD36 when oxLDL is existing."

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"To further explore the downregulation of CD36 and considering UCHL1 as a deubiquitinase, we supposed that UCHL1 promoted CD36 degradation was associated with proteasome system."

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"We next explored the molecule mechanism of reduction of CD36 protein induced by UCHL1 inhibition or knockdown."