IndraLab

Statements



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"Next, addition of MG132, a proteasome specific inhibitor, effectively blocked the reduction of USP7 associated with ECT2 depletion, suggesting that this effect was probably through a proteasome mediated protein degradation mechanism."

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"Further, downregulation of SUV39H1 protein expression in response to USP7 silencing was inhibited when cells were treated with the proteasomal inhibitor MG-132."