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N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal activates USP7. 2 / 2

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"Moreover, USP7 downregulated‐mediated AKT decreasing could be restored by MG132 (Figure 5L,M and Figure S6J,K)."

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"Next, addition of MG132, a proteasome specific inhibitor, effectively blocked the reduction of USP7 associated with ECT2 depletion, suggesting that this effect was probably through a proteasome mediated protein degradation mechanism."

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IndraLab

Statements

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal activates USP7. 2 / 2

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