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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal activates USP7. 2 / 2

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"Next, addition of MG132, a proteasome specific inhibitor, effectively blocked the reduction of USP7 associated with ECT2 depletion, suggesting that this effect was probably through a proteasome mediated protein degradation mechanism."

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"Further, downregulation of SUV39H1 protein expression in response to USP7 silencing was inhibited when cells were treated with the proteasomal inhibitor MG-132."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...