IndraLab

Statements



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"However, recent studies sug- gest that TPCK inhibits NF-KB activation by interfering IKE]-~ Regulates Persistent Activation of NF-~ B 579 LPS + CHX LPS + TPCK LPS + PDTC am ~ U ~ Sm NF-~ B DNA binding[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"TPCK and TLCK have been shown to prevent the activation of the transcription factor NF-KB by blocking the proteolytic degradation of hcBa in RAW 264.7 macrophages, human monocytes and HeLa cells (4, 1[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The protease inhibitors TLCK (N alpha-p-Tosyl-L-Lysine Chloromethyl Ketone) and TPCK (N alpha-p-Tosyl-L-Phenylalanine Chloromethyl Ketone) inhibit both p105 to p50 processing and MAD3 degradation, and also cause a complete block to NF-kappa B activation."