IndraLab

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USP50 activates NLRP3. 1 / 1
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"IL-1β ( Figures 3C-F ) and IL-18 ( Figures 3G-J ) levels measured by ELISA further corroborated the positive regulation of USP50 on bile acid-induced NLRP3 inflammasome activation.The basic levels of the members of NLRP3 inflammasome were not affected by modulating USP50 expression without TDCA treatment."