IndraLab

Statements


HDL inhibits MYD88. 5 / 5
| 3 2

reach
"In contrast, HDL pretreatment failed to significantly suppress MyD88 dependent pathway genes, such as Tnf-alpha, Il-6, and Il-1beta (XREF_FIG)."

reach
"This suggests that HDL can inhibit both the MyD88 and TRAM and TRIF actions of TLR4 activation."

reach
"It was observed that the TIR-domain-containing adapter-inducing interferon-β (TRIF)-related adaptor molecule (TRAM)/TRIF arm of the TLR4 signaling branch was significantly suppressed by HDL, suggesting that HDL inhibits both the MyD88 and the TRAM/TRIF actions of TLR4 activation [113]."

sparser
"It was observed that the TIR-domain-containing adapter-inducing interferon-β (TRIF)-related adaptor molecule (TRAM)/TRIF arm of the TLR4 signaling branch was significantly suppressed by HDL, suggesting that HDL inhibits both the MyD88 and the TRAM/TRIF actions of TLR4 activation [113]."

sparser
"It was observed that the TIR-domain-containing adapter-inducing interferon-β (TRIF)-related adaptor molecule (TRAM)/TRIF arm of the TLR4 signaling branch was significantly suppressed by HDL, suggesting that HDL inhibits both the MyD88 and the TRAM/TRIF actions of TLR4 activation [ xref ]."