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USP3 deubiquitinates SNAI1. 9 / 9
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"<span class="match term0">USP3</span> interacts directly with <span class="match term1">Snail</span> and stabilizes <span class="match term1">Snail</span> via deubiquitination"
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"34 Additionally, USP3 mediates the deubiquitylation of Snail1, stabilizing its protein levels."
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"The regulatory mechanism not only relies on the SND1-IT1/miR-1245b-5p/USP3 axis, but SND1-IT1 also recruits DDX54 to stabilize USP3, while USP3 also mediates the deubiquitination of SNAIL1 [40]."
38773075
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"Deubiquitinases (DUBs) also play an important role in the regulation of Snail1 protein stability, including USP3, USP11, USP13, DUB3, USP18, USP26, USP27X, USP37, USP47, OTUB1, and PSMD14, that have been shown to facilitate deubiquitination and stabilization of nuclear Snail1 in promoting cell proliferation, migration, and invasion ."
37833415
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"USP3 mediates SNAIL1 deubiquitination."
35739527
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"The outcome showed that USP3 mediated the deubiquitination of SNAIL1 (Fig. 7F)."
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"To sum up, USP3 mediates SNAIL1 deubiquitination."
35739527
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"Moreover, our study suggested that USP3 can mediate the deubiquitination of SNAIL1 for the first time."
35739527
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"Besides deubiquitinating Snail, USP3 can stabilize other proteins, such as Aurora A, to enhance cell growth and metastases in cancers such as esophageal squamous cell carcinoma ( Shi et al. 2021 )."
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