IndraLab

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"Corticosterone inhibits pineal NFKB leading to an enhancement of melatonin production, while tumor necrosis factor (TNF) leads to inhibition of Aa-nat transcription and the production of N-acetylserotonin in cultured glands."
20586888
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"These data suggest that increases in corticosterone may inhibit the NFKB pathway in the pineal glands from Syrian hamsters.DiscussionIn this study, we showed that maintaining Syrian hamsters in a constant light, which elevated endogenous corticosterone levels, inhibited the NFKB content in the pineal gland."
22043926
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"We show that anincrease in endogenous corticosterone inhibits NFKB pineal activation, which suggests that the pineal gland in the Syrian hamster can also be considered as a sensor for inflammation mediators.Materials and methodsAnimalsAll experiments were conducted in accordance with the European Committee Council Directive 1986 (86/609/EEC)."
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