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EGF increases the amount of COPS6. 6 / 6
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"Immunoblot analysis showed that EGF treatment increased the steady-state expression of CSN6 in DLD-1 colon cancer cells, whereas inhibition of MEK and ERK by the MEK1 inhibitor PD98059 diminished the EGF induced increase of CSN6 expression (XREF_FIG)."
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"Immunoblot analysis showed that EGF treatment increased the steady-state expression of CSN6 in DLD-1 colon cancer cells, whereas inhibition of MEK and ERK by the MEK1 inhibitor PD98059 diminished the [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, we found that EGF treatment increased the S60 phosphorylation level of CSN6 with concurrent Akt phosphorylation."
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"Treatment with calf intestinal alkaline phosphatase (CIP) reduced the EGF induced steady-state expression of CSN6, indicating that CSN6 phosphorylation is required in this process (XREF_FIG) and presumably acts through ERK."
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"Treatment with calf intestinal alkaline phosphatase (CIP) reduced the EGF induced steady-state expression of CSN6, indicating that CSN6 phosphorylation is required in this process and presumably acts [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Immunoblotting analysis showed that EGF treatment decreased the steady‐state expression of FOXO4 within 45 min (Figure  1A, Figure S1A, Supporting Information) and accelerated turnover rate of FOXO4 (Figure S1B, Supporting Information) in several CRC cell lines, whereas the EGF induced the expression of CSN6 and COP1, an E3 ligase, within that period of time (Figure 1A, Figure S1A, Supporting Information)."
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