IndraLab

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USP43 increases the amount of CTTN. 3 / 3
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"Conversely, over-expression of USP43 increased cortactin protein expression without affecting its expression at the transcriptional level (Fig. 5D, E)."
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"These results indicated that USP43 mediated the functions of Ca 2.2 in cortactin expression, invadopodia formation, ECM degradation, and metastasis."
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"We then transfected the cDNAs of these six DUBs into MDA-MB-231 cells, and immunoblotting showed that only USP43 increased cortactin expression (Supplementary Fig. 9A)."
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