IndraLab

Statements

GALNT2 glycosylates CACNA1A. 2 / 2
| 2
sparser
"In support of this finding, both GALNT1 and GALNT2 can glycosylate EA2 peptide, but only GALNT2 can glycosylate Apo C-III peptide [ xref ]."
25730904
sparser
"In QM/MM simulations of the glycosylation of the EA2 peptide by GalNAc-T2, Gomez el al. characterized a hydrogen bond between the backbone amide of Thr 0 and the β-phosphate group on UDP xref They proposed that the hydrogen bond stabilizes the transition state (TS) in “a general catalytic strategy used in peptide O-glycosylation by retaining glycosyltransferases”."
34322281