IndraLab

Statements

IL6ST binds IL15. 4 / 4
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"However IL-15-gp130 was coimmunoprecipitated with IL-15-gp130-EYFP as indicated on the right panel of xref B. We conclude that IL-15-gp130 can form homodimers on the cell surface that induce gp130-dependent but cytokine-independent signaling."
20554759
sparser
"Interestingly, only IL-15-gp130 but not IL-15-LIFR, IL-15-OSMR or IL-15-WSX1 was able to form homomeric biologically active receptor complexes that led to sustained activation of STAT3 and ERK1/2 and [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31147158
sparser
"To demonstrate the physical interaction of two IL-15-gp130 proteins, we performed coimmunoprecipitation experiments using lysates containing IL-15-gp130 and IL-15-gp130-EYFP."
20554759
sparser
"As indicated in the left panel of xref B, IL-15-gp130 was not detected after coimmunoprecipitation from lysates of single-transfected cells, indicating that IL-15-gp130 did not unspecifically interacted with anti-GFP-antibodies or protein G agarose."
20554759