IndraLab

Statements

IL15 binds IL6ST. 3 / 3
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sparser
"To demonstrate the physical interaction of two IL-15-gp130 proteins, we performed coimmunoprecipitation experiments using lysates containing IL-15-gp130 and IL-15-gp130-EYFP."
20554759
sparser
"As indicated in the left panel of xref B, IL-15-gp130 was not detected after coimmunoprecipitation from lysates of single-transfected cells, indicating that IL-15-gp130 did not unspecifically interacted with anti-GFP-antibodies or protein G agarose."
20554759
sparser
"However IL-15-gp130 was coimmunoprecipitated with IL-15-gp130-EYFP as indicated on the right panel of xref B. We conclude that IL-15-gp130 can form homodimers on the cell surface that induce gp130-dependent but cytokine-independent signaling."
20554759