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USP28 activates CD44 protein stability. 2 / 2
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eidos
"ISO attenuated CD44 protein stability by down-regulating USP28 in human BC cells Because ISO treatment not only inhibited endogenous CD44 expression but also reduced ectopic CD44 protein expression in T24T cell , the study next examined if down-regulation of CD44 expression due to ISO was a result of changes in degradation of CD44 protein ."
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eidos
"On the other hand , ISO also downregulated USP28 expression , which in turn reduced CD44 protein stability ."
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