IndraLab

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KCNH2 activates KCN. 4 / 4
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"For example, congenital long QT syndrome is caused by mutations in the human ether-a-go-go-related gene (HERG) encoding a potassium channel."
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"The human ether-a-go-go-related gene (hERG) is a cardiac repolarizer that mainly encodes a protein and also activates the rectifier potassium channel (IKr) [60]."
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"mRNA levels of the KCNH2 unit of the rapidly (I Kr) activating delayed rectifier potassium channel and KCNQ1/2 [(two members of the potassium voltage gated channel subfamily Q of the slowly (I Ks) act[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"HERG codes for a voltage activated potassium channel that is especially important during the repolarization phase of the action potential."
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