IndraLab

Statements


PRSS27 inhibits MYSM1. 1 / 1
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reach
"Compared with the full length of MYSM1, the lack of SWIRM domain had little effect on ERα-induced transactivation, while MYSM1-ΔSANT or MYSM1MPN dramatically reduced ERα action (Fig. 2C), indicating that the SANT or MPN domain is required for the co-activation function of MYSM1 on ERα-mediated transactivation.Indeed, ERα behaves in numerous biological processes through its target genes."