IndraLab

Statements

OTUD5 inhibits IRF3. 3 / 3
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sparser
"These results suggest that DUBA inhibits IRF3 by functioning as a K63-specific DUB that antagonizes the function of TRAF3."
19281271
reach
"Removal of Lys 63 -linked polyubiquitin chains from RIG-I and TRAF3 by cylindromatosis (CYLD) and deubiquitinating enzyme A (DUBA), respectively, inhibits the RIG-I-dependent activation of IRF3."
24399297
reach
"These results suggest that DUBA inhibits IRF3 by functioning as a K63 specific DUB that antagonizes the function of TRAF3."
19281271