IndraLab

Statements

Porphyrin inhibits NLRP3. 2 / 2
| 2
reach
"However, Bi et al. (2018) showed that the Mn(III) tetrakis (4-benzoic acid) porphyrin chloride (MnTABP) can significantly improve the morphology and function of mitochondria and limit the activation of NLRP3 inflammasome, finally reducing the renal injury caused by aldosterone."
32175320
reach
"But, similar to our findings in podocytes or glomeruli, a recent report provided evidence that scavenging of extracellular O 2 *- by SOD mimetic Mn (III) tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnTE-2-PyP) could prevent NLRP3 inflammasome activation in a model of hypoxia induced pulmonary hypertension [XREF_BIBR]."
24140862