IndraLab

Statements

USP39 activates FOXM1. 4 / 4
| 4
reach
"The results suggest that knockdown of USP39 inhibits the growth of HCC in vitro and in vivo, potentially through the induction of G2/M arrest by regulating the pre-mRNA splicing of FoxM1."
28413501
reach
"Mechanistically, USP39 was revealed to upregulate SIRT7 by promoting the transcriptional activity of FOXM1."
37957720
reach
"Inhibition of USP39 by siRNA has downregulated FOXM1 and in turn led to tumor volume reduction in xenograft model of HCC."
33680951
reach
"In our work, USP39 interacted with FOXM1 and promoted the splicing of FOXM1 pre-mRNA."
37957720