IndraLab

Statements


USP9X deubiquitinates E3_Ub_ligase. 2 / 2
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"However, Xie et al. found that USP9X can deubiquitinate and stabilize E3 ubiquitin ligase Smurf1 to downregulate TGF-β receptor level, which negatively regulate the TGF-β/Smad pathway [ 17 ]."

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"USP9X reduces VHL abundance by deubiquitylating SMURF1, an E3 ligase targeting VHL [39] ."