IndraLab

Statements


USP7 decreases the amount of SLC9A3. 4 / 4
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"Knockdown of USP7 or USP10 in SK-CO15 cells increased ubiquitination levels of NHE3 by 358 ± 62% or 396 ± 45%, respectively (Figure 2C)."

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"Silencing of USP7 or USP10 increased the ubiquitination levels of NHE3 compared with shCon (Figure 2B, upper panel)."

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"Knockdown of either USP7 or USP10 increased ubiquitination level of NHE3, demonstrating that these proteins deubiquitinate NHE3."

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"Knockdown of USP7 or USP10 resulted in increased NHE3 ubiquitination and decreased NHE3 expression at the surface membrane and cellular level."