IndraLab

Statements


USP19 activates SNCA. 3 / 3
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"Recently, the DUB, USP19, was shown to promote misfolded alpha-synuclein secretion [XREF_BIBR]."

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"However, under this condition, wild type (WT) USP19 is able to promote the secretion of misfolded alpha-Synuclein (alpha-Syn) in a dose dependent manner, as demonstrated previously 3."

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"Although USP19 stimulates alpha-synuclein secretion, exosome dependent tau secretion is not enhanced.113 4 Alternative Spreading Mechanisms."