IndraLab

Statements

OTUD7B activates KLF4. 3 / 3
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"Consistently, in HEK293 cells and VSMCs enforced to express OTUD7B and KLF4, OTUD7B overexpression obviously enhanced KLF4 protein stability."
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"Correspondingly, OTUD7B knockdown decreased, whereas its overexpression increased, KLF4 protein levels."
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"Our findings reveal, for the first time, that OTUD7B upregulates the level of KLF4 protein through interacting with and deubiquitylating KLF4."
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