IndraLab

Statements

eidos
"Inhibition of cIAPs or deubiquitination of RIPK1 by cylindromatosis ( CYLD ) can block the activation of NF-kappaB pathway , leading to the dissociation of RIPK1 and TRADD from the plasma membrane-associated complex28 ."
33088682
eidos
"SUMO2 and SUMO3 bind to Lysine residue 277 of NEMO and prevent its deubiquitination by CYLD ( a deubiquitinase ) and thus , causing stronger activation of IKK upon stimulation of cells with TLR4 , TLR3 , and TLR7-specific agonists [ 263 ] ."
| DOI
eidos
"SUMO2 and SUMO3 bind to Lysine residue 277 of NEMO and prevent its deubiquitination by CYLD ( a deubiquitinase ) and thus , causing stronger activation of IKK upon stimulation of cells with TLR4 , TLR3 , and TLR7-specific agonists [ 263 ] ."
| PMC