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BRD4 shRNA resembling JQ1 activates JOSD1. 1 / 1
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eidos
"Besides , we found that knockdown of BRD4 by shRNA , resembling the effect of JQ1 , inhibited the expression of JOSD1 ( Fig. 2e , f ) , while BRD4 overexpression significantly upregulated JOSD1 in HNSCC cells ( Fig. 2g , h ) , suggesting that BRD4 affected JOSD1 expression at the transcriptional level ."