IndraLab

Statements


UBB inhibits USP4. 1 / 1
| 1

reach
"Moreover, mutating such cysteine residues to alanine prevented USP4 retrieval by HA-ubiquitin, restored the ability of catalytically dead USP4 to interact with CtIP and MRN, and also restored the ability of catalytically inactive USP4 to promote DSB repair, even in the absence ofendogenous USP4."