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YOD1 inhibits IKK_complex. 2 / 2

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"Further, IL-1 triggered IKK and NF-kappaB signaling and induction of target genes is decreased by YOD1 overexpression and augmented after YOD1 depletion."

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reach

"Additionally, studies have indicated YOD1’s role of deubiquitinating proteins in response to inflammatory cytokines such as IL-1 and subsequently antagonizes IKK/NF-kB signaling (18)."

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IndraLab

Statements

YOD1 inhibits IKK_complex. 2 / 2

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