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USP2 activates Imd. 2 / 2

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"Surprisingly, USP2 also targets Imd for degradation, a function which, from our proteomic analysis of USP2 partners and subsequent co-immunoprecipitation experiments, likely occurs at the level of the proteasome."

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"We further show that USP2 prevents the constitutive activation of signalling by promoting Imd proteasomal degradation."

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IndraLab

Statements

USP2 activates Imd. 2 / 2

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