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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP3 decreases the amount of IFNB1. 3 / 3

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"Ectopic expression of USP3 inhibited IFN-beta promoter activity in cells treated with high molecular weight (HMW) poly (I : C), whereas gene silencing of USP3 enhanced IFN-beta protein expression under similar treatment."

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"Gene silencing of USP3 enhanced IFN-beta protein expression under similar treatments."

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"Conversely, the silencing of USP3 enhanced the phosphorylation of IRF3 and IFN-beta protein expression under similar conditions."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP3 decreases the amount of IFNB1. 3 / 3

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