IndraLab

Statements


VEGF phosphorylates KCNA2. 2 / 2
| 1 1

rlimsp
"Finally, the enhancement of the tyrosine phosphorylation of the channel by VEGF in neuronal cells was significantly attenuated in the presence of wortmannin, an inhibitor of phosphatidylinositol 3-kinase (PI3-K), or genestin, an inhibitor of tyrosine kinase, thus suggesting that the phosphorylation of Kv 1.2 induced by VEGF is mechanistically linked to the PI3-K pathway."

sparser
"In contrast, in SH-SY5Y subjected to hypoxia and glucose deprivation, attenuation of cell death was achieved by tyrosine phosphorylation of Kv1.2 by VEGF [ xref ]."