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Glucose inhibits IRF3. 1 / 1
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"Calcium disruption (as through the SERCA pump inhibitor thapsigargin) and oxygen glucose deprivation activate IRF3 through a STING dependent mechanism, whereas agents that disrupt N linked glycosylation (e.g., tunicamycin) appear to utilize a STING independent, but Site-1 and Site-2 protease (ATF6?)"