A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

BRAF binds KRAS and RAF1. 2 / 2
| 2
sparser
"It also strongly stimulated KRASBRAF and KRASCRAF interactions and inhibited RAF intramolecular interaction with potencies similar to GDC-0879 (Fig.  xref , f; Supplementary Fig.  xref )."
sparser
"Consistent with this, the interaction of KRAS G12V with BRAF and CRAF gatekeeper mutants was resistant to GDC-0879 (type I), but not to AZ-628 (type II) in BRET dose-response experiments (Fig.  xref and Supplementary Fig.  xref )."