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USP1 increases the amount of USP1. 1 / 1

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"The important regulatory role of USP1 in DNA repair, supported by the finding that USP1 gene knockout in model systems leads to DNA damage hypersensitivity [XREF_BIBR - XREF_BIBR], together with the observation that USP1 is frequently overexpressed in tumors, suggests that USP1 could be a relevant target for cancer therapy, whose inhibition might contribute to overcome chemoresistance."

23937906

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IndraLab

Statements

USP1 increases the amount of USP1. 1 / 1

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