IndraLab

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OTUD4 deubiquitinates SNAI1. 3 / 3
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"Meanwhile, the depletion of OTUD4 in MDA-MB-231 cells significantly increased Snail1 ubiquitination ( Fig. 4 C)."
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"Together, these results demonstrate that OTUD4 is a bona fide deubiquitinase targeting Snail1 for deubiquitination and stabilization.Since OTUD4 deubiquitinates and stabilizes Snail1, we next investig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"To sum up, our study demonstrated that OTUD4 deubiquitinates and stabilizes Snail1, thereby promoting metastasis of TNBC and targeting OTUD4 might be a potential therapeutic strategy in the treatment [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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