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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TNFAIP3 activates IL1R1. 1 / 1

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"One group found, upon overexpression of TNFAIP3 in an HEK293 cell line that also overexpressed the IL-1R, that TNFR1 complexes still contained polyubiquitinated RIP1 upon TNFalpha binding even though NF-kappaB was strongly inhibited."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...