IndraLab

Statements

USP3 activates SNAI1. 3 / 3
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"Implications : Our study establishes USP3 mediated Snail stabilization as an important mechanism underlying GBM invasion and progression, and provides a rationale for potential therapeutic interventions in the treatment of GBM."
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"The result displayed that, USP3 ablation inhibited SNAIL1 protein degradation (Fig. 7H)."
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"For example, USP3, USP11, and USP29 stimulate EMT in glioblastoma cells, as well as in ovarian or gastric cancer cells, respectively, by stabilizing Snail [80–82] ."
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