IndraLab

Statements

GEMIN4 binds PLEK and VCPIP1. 3 / 3
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"However, it has also been shown that ATP is required for the p97, p47, and VCIP135 complex to dissociate from Syn5 [XREF_BIBR]."
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"Other studies have confirmed that the p97, p47, and VCIP135 complex is required for cell-cycle-dependent reformation of the ER network and that p97-p47-mediated reassembly of Golgi cisternae requires the deubiquitinating activity of VCIP135 [XREF_BIBR, XREF_BIBR]."
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"The ubiquitin moieties on these substrates, added by HACE1 during mitosis, likely serve as receptors for the p97, p47, and VCIP135 complex at the end of mitosis to carry on fusion reactions after the removal of the ubiquitin tags by VCIP135 (XREF_FIG) XREF_BIBR, XREF_BIBR."
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