IndraLab

Statements

G_alpha inhibits KCNK2. 3 / 3
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"Conversely, TREK-1 channels are inhibited by cAMP and following Gαq and Gαs activation [16,22,26]."
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"Gα receptors uniformly inhibit TASK and TREK-1 channels, but by different mechanisms."
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"TREK1 activity is inhibited by the activation of Galpha q -coupled receptors, such as the thyrotropin releasing hormone receptor 1 (TRHR1) and the Orexin receptor (Orx1R), but is enhanced by the Galpha i -coupled receptors, including the metabotropic glutamate receptor 4 (mGluR4)."
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