IndraLab

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"HCQ alone enhanced ABCA3 vesicle size and PC recycling, and its combination with CsA strongly enhanced ABCA3 vesicle size.In G210C, CsA alone did not correct % WT‐like cells to normal range, but in combination with HCQ did (Figure 3A)."

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"Treatment with methylprednisolone or hydroxychloroquine did not correct the loss of PC in SP-C A116D expressing cells, although a significant increase of PC was noted in the cells treated with hydroxychloroquine."