IndraLab

Statements

PXN binds USP13. 7 / 7
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sparser
"Furthermore, Paxillin and Paxillin(Y118A) interacted with USP13, but Paxillin(Y31A) failed to associate with USP13 (Fig.  xref l), implicating that Paxillin Y31 phosphorylation is important for USP13-Paxillin interaction."
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"USP13 interacts with Paxillin and NLRP3, phosphorylation of Paxillin at Y31 is important for Paxillin-USP13 interaction, and USP13 is essential for Paxillin-mediated NLRP3 deubiquitination upon ATP treatment."
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sparser
"Moreover, Co-IP assays showed that Paxillin and USP13 interacted with each other (Fig.  xref d, e)."
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"Moreover, the domains of USP13 required for USP13-NLRP3 interaction and USP13-Paxillin association were assessed by constructing and analyzing plasmids encoding for WT USP13(1–863) and four truncated proteins (Fig.  xref i)."
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biogrid
No evidence text available
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sparser
"Additionally, USP13(1–863) and USP13(1–300) interacted with Paxillin, but USP13(301–624), USP13(301–863), and USP13(625–863) could not interact with Paxillin (Fig.  xref k), indicating that 1aa–300aa of USP13 is involved in USP13-Paxillin interaction."
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biogrid
No evidence text available
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