IndraLab

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CACNA1A activates ion channel. 7 / 7
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sparser
"Voltage-dependent activation and deactivation of ion channels in the Shaker superfamily were thought to be mainly determined by the transmembrane channel domains."
9635749
sparser
"In a recent study ( xref ), we have shown that the net free energy associated with voltage-dependent activation of an ion channel can be estimated by extracting the median voltage of activation from the Q-V curve using the relation:"
23250866
sparser
"Our simulations provide insights into the Shaker VSD permeation pathway, the protein-ion interactions that control permeation kinetics, and the mechanism of voltage-dependent activation of voltage-gated ion channels."
28074656
reach
"These differences are probably due to genetic expression, which is affected by other genes, the environment, hormones, etc.FHM1 has been identified as an ion channel disease caused by CACNA1A gene mutations."
31824404
sparser
"The Boltzan sigmoid equation is the one that describes voltage-dependent activation of ion channels, where conductance ( Y ) is described as a function of the membrane potential ( X )."
10529010
reach
"Full-length CACNA1A mRNA produces the alpha1A ion channel subunit."
25108806
sparser
"The simulations of guanidinium ion permeation also provide new insights into the mechanism of voltage-dependent activation of voltage-gated ion channels."
28074656