IndraLab

Statements

USP15 binds USP7. 12 / 12
2 | 3 7
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"Therefore, our results demonstrate for the first time the activation of the USP7-USP15 axis in MDS, indicating its role in controlling genomic instability in this disease."
37373211
biogrid
No evidence text available
28276505
biogrid
No evidence text available
22626734
reach
"In order to disturb specific interactions between the Ub structure and USP7 and USP15, we incorporated mutations in the sequence of this mutant, (M6)."
32110315
sparser
"In addition to USP15, USP7 was also found to deubiquitinate MDM2 [ xref ]; furthermore, a previous study demonstrated the physical interaction between USP7 and USP15 [ xref ]."
38715050
sparser
"These findings suggest that the differential expression of the USP15-USP7 axis and UBE2T may play an important role in controlling genomic instability and the chromosomal abnormalities that are a striking characteristic of MDS."
37373211
sparser
"The USP15-USP7 Axis Is Downregulated in De Novo Brazilian MDS Patients."
37373211
reach
"In addition to USP15, USP7 was also found to deubiquitinate MDM2 [73]; furthermore, a previous study demonstrated the physical interaction between USP7 and USP15 [74]."
38715050
sparser
"Our results highlight that the differential gene expression of the USP15-USP7 axis and UBE2T can play a crucial role in the control of genomic instability, which is one of the most significant features of MDS, particularly chromosomal abnormalities."
37373211
sparser
"In myelodysplastic neoplasm, the differential expression of USP15-USP7 axis and UBE2T may predict pathogenesis and poor prognosis of patients ( xref )."
40918133
sparser
"A protein-protein interaction screen study has revealed the physical interaction between USP15 and USP7, although the functional significance remains to be further studied xref ."
24777531
reach
"A protein protein interaction screen study has revealed the physical interaction between USP15 and USP7, although the functional significance remains to be further studied 36."
24777531