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USP53 increases the amount of MSR1. 2 / 2

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"Importantly, USP53 knockdown significantly attenuated the rDKK1-induced upregulation of SR-A expression in SMCs (Figure 6J), and reduced the rDKK1-induced lipid accumulation and DIL-oxLDL uptake (Figure 6K, 6L)."

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"USP53 upregulates the SR-A expression via a deubiquitinating function, leading to stronger and more stable promotion of foam cell formation and AS."

38904030

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IndraLab

Statements

USP53 increases the amount of MSR1. 2 / 2

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