IndraLab

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IL17A increases the amount of TNFAIP3. 4 / 5
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"[49] Additionally, IL-17 induces the expression of the TNFAIP3 gene."
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"In the presence of high glucose, IL-17A induced higher mRNA levels of TNFAIP3 and ZC3H12A ( Fig. 2 C), but not TNIP1 and USP25 (data not shown)."
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"IL-17 induces expression of Tnfaip3 mRNA and A20 protein levels, which triggers deubiquitination of TRAF6 and downregulation of NF-kappaB and MAPK activation (particularly JNK)."
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"We demonstrated that IL-17 stimulates TNFAIP3 expression."
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