IndraLab

Statements

KCNH2 activates HIF. 2 / 2
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sparser
"This signaling pathway has novel features in that the integrin- and hERG1-dependent activation of HIF (i) is triggered in normoxia, especially after CRC cells have experienced a hypoxic stage, (ii) involves NF-kB and (iii) is counteracted by an active p53."
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reach
"In other words, when the p53 centered control of cellular apoptosis and shortage of HIF activity was impaired, the ECM and hERG1 dependent stimulation of HIF activity was stronger."
24270902