IndraLab

Statements

USP8 activates E3_Ub_ligase. 2 / 2
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"One study showed that USP8 acts downstream of PTEN to enhance the ability of the E3 ligase Itch to reduce cFLIP stability and increase tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity in human glioblastoma multiforme cells [97]."
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"Ubiquitin-specific protease 8 (USP8) belongs to ubiquitin proteasome system and mediates the stability of E3 ligases."
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