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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Infections increases the amount of USP18. 2 / 3

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"Ye et al. (2021) demonstrated that DENV-2 infection increased USP18 expression; USP18 overexpression enhanced DENV-2 replication, while USP18 silencing inhibited DENV-2 replication by activating the IFN-α-mediated JAK/STAT signaling pathway."

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"Here we studied the role of ISG15-specific ubiquitin-like protease 43 (USP18) in HIV-1 innate immune sensing.HIV-1 infection induces the expression of USP18 in PMA-differentiated THP-1 cells."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...