IndraLab

Statements


TNF decreases the amount of AQP1. 9 / 9
| 9

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"As seen in XREF_FIG A, AQP1 mRNA expression in HK2 cells was downregulated by a combined TNFalpha plus IL-1beta treatment."

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"Moreover, the inhibition of IL-1β and TNF-α or corticosteroid treatment could up-regulate AQP1 expression and promote edema clearance reducing lung injury [34,42] ."

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"3, 4, 5, mRNA, and protein levels of AQP1, -3 and -4 were significantly reduced by H O , TNFα, and HMGB1, respectively."
| PMC

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"The results, depicted in XREF_FIG B, show that TNF-alpha treatment downregulates the expression of both AQP1 and AQP5 (0.183 +/- 0.01 and 0.083 +/- 0.01-fold p < 0.001, respectively), as previously reported [XREF_BIBR]."

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"No significant differences in Aqp-1 were found for untreated cells between the 24 hour and 1 week time points, but LPS and TNF-alpha treated cells had significantly reduced Aqp-1 expression at the recovery time point as compared with 24 hour treatment (p < 0.01)."

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"Furthermore, our results show that TNF-alpha treatment downregulates AQP1 expression in endothelial cells, suggesting that SAH induced inflammatory activation might be responsible for the observed SAH mediated decrease of AQP1."

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"TNF-alpha Decreases AQP1 and AQP5 Expression in BEAS 2B Cells."

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"Interestingly, B6-RPE07 cells expressed AQP1 in vitro, and TNF-alpha downregulated AQP1 protein expression in those cells."

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"Suppression of AQP1 transcription by inflammatory TNF-alpha is restrained by KLF2."