IndraLab

Statements



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"Transwell assay revealed that there were fewer migratory cells in the of USP14 inhibitor-treated group than in the control group, suggesting that USP14 inhibition impairs cell migration (Fig. 3H)."

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"Functionally, USP14 overexpression reduced apoptosis and increased cell migration, invasion, and EMT in vivo and ex vivo."

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"By detecting cell migration and invasion by Transwell assay, it was found that USP14 knockdown reduced EC cell migration and invasion (Figure 4E)."

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"Moreover, knockdown of USP14 inhibited cell migration, however, overexpression of wild-type USP14 but not USP14 mutants promoted cell migration."

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"Wound-healing assays showed that the overexpression of USP14 promoted the HNSCC cell migration capacity, while the USP14 mutant type did not (Figure 4E), and the quantitation is shown in Figure S2C."

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"The results showed that inhibition of USP14 significantly decreased the cell migration in Ishikawa cells (Fig. 6, A and B)."

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"The results demonstrated that USP14 depletion inhibited cell migration, and conversely, ectopic expression of USP14 promoted cell migration in the presence of E2 (Fig. 6, E–H)."

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"Overexpressing USP14 reduced apoptosis and promoted EC cell migration and invasion."