IndraLab

Statements

Sensor activates KCNQ1. 4 / 4
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"KCNE3 acts by promoting voltage sensor activation in KCNQ1."
26668384
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"In addition, it has been shown that voltage sensor activation in KCNQ1 proceeds through an intermediate step before reaching full activation XREF_BIBR."
28383569
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"Together our findings suggest that altered charge-pair interactions within the voltage sensor module of KCNQ1 subunits may account for slowed I (Ks) deactivation induced by S140 or V141."
18599533
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"In summary, our study demonstrates that KCNE1 alters the kinetics and voltage dependence of voltage sensor activation and channel opening of KCNQ1 channels."
24769622