IndraLab

Statements


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sparser
"MIF binds to JUN-activation domain-binding protein 1 (JAB1), preventing JAB1-induced activation of JUN and JAB1-induced degradation of the cell-proliferation inhibitor KIP1, thereby leading to cell-cycle arrest and apoptosis."

reach
"MIF binds to JUN-activation domain-binding protein 1 (JAB1), preventing JAB1-induced activation of JUN and JAB1-induced degradation of the cell-proliferation inhibitor KIP1, thereby leading to cell-cycle arrest and apoptosis."

sparser
"JAB1 activates JUN N-terminal kinase (JNK) to phosphorylate JUN and so functions as a co-activator of activator protein 1 (AP1) -a transcription factor that is implicated in cell growth, transformation and cell death 54 ."